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Answer - Posted in: aclasta, injection - Answer: Aclasta is usually given by infusion into a vein once a year.
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FUNDING Funded by: Helsinn Healthcare SA Affiliation of contact author: Bergamo Hospital, Italy Affiliation of statistician: unclear Affiliation of study administrator: unclear No.
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Intervention details Outcome assessment Allocated: a 58, b 53, c 60 Completed: a 46, b 25, c 45 Drop-out: a 12, b 28, c 15 Assessed for GI symptoms: a 58, b 53, c 60 Outcomes reported: GI symptoms, endoscopic ulcers, anaemia, GI drop-outs How were adverse events assessed: participants asked if there had been any problems since last visit How was compliance assessed: tablet count Risk factors: history of ulcers (1 year or more ago); a 10, b 14, c 14 all participants aged 60 years or more CVD: a 0, b 0 FUNDING Funded by: SmithKline Beecham Pharmaceuticals Affiliation of contact author: Arthritis Center, Phoenix, AZ, USA Affiliation of statistician: unclear Affiliation of trial administrator: unclear No.
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Risk factors: concomitant use of corticosteroids: a 0, b0 FUNDING Funded by: in part by a grant from Searle Affiliation of contact author: Université Réné Descartes, Paris, France Affiliation of statistician: unclear Affiliation of trial administrator: unclear No.
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Intervention details Outcome assessment Allocated: a 181, b 175, c 184, d 177 Completed: a 128, b 105, c 121, d 119 Drop-out: a 53, b 70, c 63, d 58 Assessed: a 180, b 174, c 184, d 177 Outcomes reported: mortality, serious GI complications, symptomatic ulcers, QoL, GI symptoms, occult bleeding, GI drop-outs How were adverse events assessed: diary cards How was compliance assessed: not stated Risk factors: history of PUBs: a 18, b 21, c 16, d 19 concomitant use of corticosteroids: a 53, b 57, c 65, d 47 FUNDING Funded by: Boehringer Ingelheim Pharmaceuticals Affiliation of contact author: Virginia Mason Research Center, Seattle, WA, USA Affiliation of statistician: unclear Affiliation of trial administrator: unclear No.
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